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Notch–RBP-J signaling controls the homeostasis of CD8(−) dendritic cells in the spleen

Signaling through Notch receptors and their transcriptional effector RBP-J is essential for lymphocyte development and function, whereas its role in other immune cell types is unclear. We tested the function of the canonical Notch–RBP-J pathway in dendritic cell (DC) development and maintenance in v...

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Detalles Bibliográficos
Autores principales: Caton, Michele L., Smith-Raska, Matthew R., Reizis, Boris
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118632/
https://www.ncbi.nlm.nih.gov/pubmed/17591855
http://dx.doi.org/10.1084/jem.20062648