CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance

Hyper-IgM (HIGM) syndromes are primary immunodeficiencies characterized by defects of class switch recombination and somatic hypermutation. HIGM patients who carry mutations in the CD40-ligand (CD40L) gene expressed by CD4(+) T cells suffer from recurrent infections and often develop autoimmune diso...

Descripción completa

Detalles Bibliográficos
Autores principales: Hervé, Maxime, Isnardi, Isabelle, Ng, Yen-shing, Bussel, James B., Ochs, Hans D., Cunningham-Rundles, Charlotte, Meffre, Eric
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118633/
https://www.ncbi.nlm.nih.gov/pubmed/17562816
http://dx.doi.org/10.1084/jem.20062287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118633/
https://www.ncbi.nlm.nih.gov/pubmed/17562816
http://dx.doi.org/10.1084/jem.20062287

Ejemplares similares