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Activation phenotype, rather than central– or effector–memory phenotype, predicts the recall efficacy of memory CD8(+) T cells

The contributions of different subsets of memory CD8(+) T cells to recall responses at mucosal sites of infection are poorly understood. Here, we analyzed the CD8(+) T cell recall responses to respiratory virus infection in mice and demonstrate that activation markers, such as CD27 and CD43, define...

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Detalles Bibliográficos
Autores principales: Hikono, Hirokazu, Kohlmeier, Jacob E., Takamura, Shiki, Wittmer, Susan T., Roberts, Alan D., Woodland, David L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118640/
https://www.ncbi.nlm.nih.gov/pubmed/17606632
http://dx.doi.org/10.1084/jem.20070322