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BAFF and MyD88 signals promote a lupuslike disease independent of T cells

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the production of autoantibodies. However, the underlying cause of disease appears to relate to defects in T cell tolerance or T cell help to B cells. Transgenic (Tg) mice overexpressing the cytokine B cell–activati...

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Detalles Bibliográficos
Autores principales: Groom, Joanna R., Fletcher, Carrie A., Walters, Stacey N., Grey, Shane T., Watt, Sally V., Sweet, Mathew J., Smyth, Mark J., Mackay, Charles R., Mackay, Fabienne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118661/
https://www.ncbi.nlm.nih.gov/pubmed/17664289
http://dx.doi.org/10.1084/jem.20062567