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Receptor editing: How B cells stay tolerant
In 1993, David Nemazee and Martin Weigert independently showed that autoreactive B cells could proofread, alter, and reexpress modified receptors to become nonautoreactive. This process, called “receptor editing,” has since gained prominence as the main mechanism of B cell tolerance.
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118665/ https://www.ncbi.nlm.nih.gov/pubmed/17823990 http://dx.doi.org/10.1084/jem.2048fta |