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Signaling through FcγRIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation

Although inhibitory Fcγ receptors have been demonstrated to promote mucosal tolerance, the role of activating Fcγ receptors in modulating T helper type (Th)2-dependent inflammatory responses characteristic of asthma and allergies remains unclear. Here, we demonstrate that signaling via activating Fc...

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Detalles Bibliográficos
Autores principales: Bandukwala, Hozefa S., Clay, Bryan S., Tong, Jiankun, Mody, Purvi D., Cannon, Judy L., Shilling, Rebecca A., Verbeek, J. Sjef, Weinstock, Joel V., Solway, Julian, Sperling, Anne I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118666/
https://www.ncbi.nlm.nih.gov/pubmed/17664287
http://dx.doi.org/10.1084/jem.20061134