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Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

Liver-derived acute phase proteins (APPs) emerged as powerful predictors of cardiovascular disease and cardiovascular events, but their functional role in atherosclerosis remains enigmatic. We report that the gp130 receptor, which is a key component of the inflammatory signaling pathway within hepat...

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Detalles Bibliográficos
Autores principales: Luchtefeld, Maren, Schunkert, Heribert, Stoll, Monika, Selle, Tina, Lorier, Rachel, Grote, Karsten, Sagebiel, Christian, Jagavelu, Kumaravelu, Tietge, Uwe J.F., Assmus, Ulrike, Streetz, Konrad, Hengstenberg, Christian, Fischer, Marcus, Mayer, Björn, Maresso, Karen, El Mokhtari, Nour Eddine, Schreiber, Stefan, Müller, Werner, Bavendiek, Udo, Grothusen, Christina, Drexler, Helmut, Trautwein, Christian, Broeckel, Ulrich, Schieffer, Bernhard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118681/
https://www.ncbi.nlm.nih.gov/pubmed/17664290
http://dx.doi.org/10.1084/jem.20070120