Cargando…

Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man

Liver-derived acute phase proteins (APPs) emerged as powerful predictors of cardiovascular disease and cardiovascular events, but their functional role in atherosclerosis remains enigmatic. We report that the gp130 receptor, which is a key component of the inflammatory signaling pathway within hepat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luchtefeld, Maren, Schunkert, Heribert, Stoll, Monika, Selle, Tina, Lorier, Rachel, Grote, Karsten, Sagebiel, Christian, Jagavelu, Kumaravelu, Tietge, Uwe J.F., Assmus, Ulrike, Streetz, Konrad, Hengstenberg, Christian, Fischer, Marcus, Mayer, Björn, Maresso, Karen, El Mokhtari, Nour Eddine, Schreiber, Stefan, Müller, Werner, Bavendiek, Udo, Grothusen, Christina, Drexler, Helmut, Trautwein, Christian, Broeckel, Ulrich, Schieffer, Bernhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118681/ https://www.ncbi.nlm.nih.gov/pubmed/17664290 http://dx.doi.org/10.1084/jem.20070120

Ejemplares similares

Gp130-Dependent Release of Acute Phase Proteins Is Linked to the Activation of Innate Immune Signaling Pathways
por: Luchtefeld, Maren, et al.
Publicado: (2011)

Role of Suppressor of Cytokine Signaling-1 In Murine Atherosclerosis
por: Grothusen, Christina, et al.
Publicado: (2012)

MAP-Kinase Activated Protein Kinase 2 Links Endothelial Activation and Monocyte/macrophage Recruitment in Arteriogenesis
por: Limbourg, Anne, et al.
Publicado: (2015)

Differential Role of gp130-Dependent STAT and Ras Signalling for Haematopoiesis Following Bone-Marrow Transplantation
por: Kroy, Daniela C., et al.
Publicado: (2012)

Common Polymorphisms Influencing Serum Uric Acid Levels Contribute to Susceptibility to Gout, but Not to Coronary Artery Disease
por: Stark, Klaus, et al.
Publicado: (2009)

Modulation of Insulin Resistance, Dyslipidemia and Serum Metabolome in iNOS Knockout Mice following Treatment with Nitrite, Metformin, Pioglitazone, and a Combination of Ampicillin and Neomycin
por: Aggarwal, Hobby, et al.
Publicado: (2021)

Targeting Tumor Necrosis Factor-α with Adalimumab: Effects on Endothelial Activation and Monocyte Adhesion
por: Oberoi, Raghav, et al.
Publicado: (2016)

Hepatic Tissue Environment in NEMO-Deficient Mice Critically Regulates Positive Selection of Donor Cells after Hepatocyte Transplantation
por: Kaldenbach, Michaela, et al.
Publicado: (2014)

Functional evaluation of GUCY1A3 mutations associated with myocardial infarction risk
por: Wobst, Jana, et al.
Publicado: (2015)

Systemic Insulin Resistance and Metabolic Perturbations in Chow Fed Inducible Nitric Oxide Synthase Knockout Male Mice: Partial Reversal by Nitrite Supplementation
por: Aggarwal, Hobby, et al.
Publicado: (2020)

One year VARC-2-defined clinical outcomes after transcatheter aortic valve implantation with the SAPIEN 3
por: Pellegrini, Costanza, et al.
Publicado: (2019)

FGF21 Promotes Endothelial Cell Angiogenesis through a Dynamin-2 and Rab5 Dependent Pathway
por: Yaqoob, Usman, et al.
Publicado: (2014)

Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia
por: Brænne, Ingrid, et al.
Publicado: (2014)

Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease
por: Oberoi, Raghav, et al.
Publicado: (2015)

Vancomycin-Induced Modulation of Gram-Positive Gut Bacteria and Metabolites Remediates Insulin Resistance in iNOS Knockout Mice
por: Aggarwal, Hobby, et al.
Publicado: (2022)

Fecal Eosinophil Cationic Protein Is a Diagnostic and Predictive Biomarker in Young Adults with Inflammatory Bowel Disease
por: Abedin, Nada, et al.
Publicado: (2019)

Experimental liver fibrosis research: update on animal models, legal issues and translational aspects
por: Liedtke, Christian, et al.
Publicado: (2013)

Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study
por: Stark, Klaus, et al.
Publicado: (2008)

One‐year clinical outcome with a novel self‐expanding transcatheter heart valve
por: Pellegrini, Costanza, et al.
Publicado: (2019)

Circulating Brain‐Derived Neurotrophic Factor Concentrations and the Risk of Cardiovascular Disease in the Community
por: Kaess, Bernhard M., et al.
Publicado: (2015)

Akutes Leberversagen: Übersicht zur aktuellen Diagnostik und Therapie
por: Streetz, K.L., et al.
Publicado: (2013)

Investigating the impact of a mutation in PDE5A on myocardial infarction
por: Dang, Tan A, et al.
Publicado: (2015)

Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance
por: Kanuri, Babu Nageswararao, et al.
Publicado: (2017)

Corrigendum: Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance
por: Kanuri, Babu Nageswararao, et al.
Publicado: (2017)

Concerns about renal safety of HES 130
por: Wiedermann, Christian J, et al.
Publicado: (2013)

Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis
por: Vlacil, Ann-Kathrin, et al.
Publicado: (2020)

Experimental Gingivitis Induces Systemic Inflammatory Markers in Young Healthy Individuals: A Single-Subject Interventional Study
por: Eberhard, Jörg, et al.
Publicado: (2013)

Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease
por: Witten, Anika, et al.
Publicado: (2022)

Genetic variants in guanylyl cyclase and phoshodiesterase affecting coronary disease risk
por: Schunkert, Heribert
Publicado: (2013)

Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)
por: Schulte, Dominik M., et al.
Publicado: (2022)

c-Met Signaling Protects from Nonalcoholic Steatohepatitis- (NASH-) Induced Fibrosis in Different Liver Cell Types
por: Drescher, Hannah K., et al.
Publicado: (2018)

Distinct Patterns of IgG and IgA against Food and Microbial Antigens in Serum and Feces of Patients with Inflammatory Bowel Diseases
por: Frehn, Lisa, et al.
Publicado: (2014)

Extracellular Ribosomal RNA Acts Synergistically with Toll-like Receptor 2 Agonists to Promote Inflammation
por: Grote, Karsten, et al.
Publicado: (2022)

C-Reactive Protein and Coronary Heart Disease: All Said—Is Not It?
por: Strang, Frederik, et al.
Publicado: (2014)

Integrating Genes Affecting Coronary Artery Disease in Functional Networks by Multi-OMICs Approach
por: Vilne, Baiba, et al.
Publicado: (2018)

Targeting ADAMTS-7: a vaccination against atherosclerosis – and its complications?
por: Kessler, Thorsten, et al.
Publicado: (2023)

Inhibitors of the renin–angiotensin system and SARS-CoV-2 infection
por: Kessler, Thorsten, et al.
Publicado: (2020)

Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies
por: Kessler, Thorsten, et al.
Publicado: (2021)

RAAS inhibition and beyond—cardiovascular medications in patients at risk of or affected by COVID-19
por: Dutsch, Alexander, et al.
Publicado: (2023)

Toll-Like Receptors in Angiogenesis
por: Grote, Karsten, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pgaiibj0rb3m3oommhapmm8fcs