Cross-competition of CD8(+) T cells shapes the immunodominance hierarchy during boost vaccination

CD8(+) T cell responses directed against multiple pathogen-derived epitopes are characterized by defined immunodominance hierarchy patterns. A possible explanation for this phenomenon is that CD8(+) T cells of different specificities compete for access to epitopes on antigen-presenting cells, and th...

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Detalles Bibliográficos
Autores principales: Kastenmuller, Wolfgang, Gasteiger, Georg, Gronau, Julian H., Baier, Robert, Ljapoci, Ronny, Busch, Dirk H., Drexler, Ingo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118691/
https://www.ncbi.nlm.nih.gov/pubmed/17709425
http://dx.doi.org/10.1084/jem.20070489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118691/
https://www.ncbi.nlm.nih.gov/pubmed/17709425
http://dx.doi.org/10.1084/jem.20070489

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