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Cross-competition of CD8(+) T cells shapes the immunodominance hierarchy during boost vaccination

CD8(+) T cell responses directed against multiple pathogen-derived epitopes are characterized by defined immunodominance hierarchy patterns. A possible explanation for this phenomenon is that CD8(+) T cells of different specificities compete for access to epitopes on antigen-presenting cells, and th...

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Detalles Bibliográficos
Autores principales:	Kastenmuller, Wolfgang, Gasteiger, Georg, Gronau, Julian H., Baier, Robert, Ljapoci, Ronny, Busch, Dirk H., Drexler, Ingo
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118691/ https://www.ncbi.nlm.nih.gov/pubmed/17709425 http://dx.doi.org/10.1084/jem.20070489

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