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MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival

The innate immune system relies on evolutionally conserved Toll-like receptors (TLRs) to recognize diverse microbial molecular structures. Most TLRs depend on a family of adaptor proteins termed MyD88s to transduce their signals. Critical roles of MyD88-1–4 in host defense were demonstrated by defec...

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Detalles Bibliográficos
Autores principales: Kim, Younghwa, Zhou, Ping, Qian, Liping, Chuang, Jen-Zen, Lee, Jessica, Li, Chenjian, Iadecola, Costantino, Nathan, Carl, Ding, Aihao
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118693/
https://www.ncbi.nlm.nih.gov/pubmed/17724133
http://dx.doi.org/10.1084/jem.20070868