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Progressive CD4(+) central–memory T cell decline results in CD4(+) effector–memory insufficiency and overt disease in chronic SIV infection
Primary simian immunodeficiency virus (SIV) infections of rhesus macaques result in the dramatic depletion of CD4(+) CCR5(+) effector–memory T (T(EM)) cells from extra-lymphoid effector sites, but in most infections, an increased rate of CD4(+) memory T cell proliferation appears to prevent collapse...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118701/ https://www.ncbi.nlm.nih.gov/pubmed/17724130 http://dx.doi.org/10.1084/jem.20070567 |
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por Okoye, Afam, Meier-Schellersheim, Martin, Brenchley, Jason M., Hagen, Shoko I., Walker, Joshua M., Rohankhedkar, Mukta, Lum, Richard, Edgar, John B., Planer, Shannon L., Legasse, Alfred, Sylwester, Andrew W., Piatak, Michael, Lifson, Jeffrey D., Maino, Vernon C., Sodora, Donald L., Douek, Daniel C., Axthelm, Michael K., Grossman, Zvi, Picker, Louis J.
Publicado 2007
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Publicado 2007
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Texto