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Uncovering the dark side of TNF
In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified “cachectin.” They soon found out that their malevolent cytokine already had another name—tumor necrosis factor (TNF)—and was being lauded as a poten...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118707/ https://www.ncbi.nlm.nih.gov/pubmed/17912767 http://dx.doi.org/10.1084/jem.2049fta |