Uncovering the dark side of TNF

In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified “cachectin.” They soon found out that their malevolent cytokine already had another name—tumor necrosis factor (TNF)—and was being lauded as a poten...

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Detalles Bibliográficos
Autor principal: Bashyam, Hema
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
From the Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118707/
https://www.ncbi.nlm.nih.gov/pubmed/17912767
http://dx.doi.org/10.1084/jem.2049fta
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author Bashyam, Hema
author_facet Bashyam, Hema
author_sort Bashyam, Hema
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description In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified “cachectin.” They soon found out that their malevolent cytokine already had another name—tumor necrosis factor (TNF)—and was being lauded as a potential antitumor agent.
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spelling pubmed-21187072008-03-03 Uncovering the dark side of TNF Bashyam, Hema J Exp Med From the Archive In the early 1980s, in search of the cytokine that triggers disease- associated weight loss and lethal shock, Anthony Cerami and Bruce Beutler purified “cachectin.” They soon found out that their malevolent cytokine already had another name—tumor necrosis factor (TNF)—and was being lauded as a potential antitumor agent. The Rockefeller University Press 2007-09-03 /pmc/articles/PMC2118707/ /pubmed/17912767 http://dx.doi.org/10.1084/jem.2049fta Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle From the Archive
Bashyam, Hema
Uncovering the dark side of TNF
title Uncovering the dark side of TNF
title_full Uncovering the dark side of TNF
title_fullStr Uncovering the dark side of TNF
title_full_unstemmed Uncovering the dark side of TNF
title_short Uncovering the dark side of TNF
title_sort uncovering the dark side of tnf
topic From the Archive
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118707/
https://www.ncbi.nlm.nih.gov/pubmed/17912767
http://dx.doi.org/10.1084/jem.2049fta
work_keys_str_mv AT bashyamhema uncoveringthedarksideoftnf

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