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A role for AID in chromosome translocations between c-myc and the IgH variable region

Chromosome translocations between oncogenes and the region spanning the immunoglobulin (Ig) heavy chain (IgH) variable (V), diversity (D), and joining (J) gene segments (Ig V-J(H) region) are found in several mature B cell lymphomas in humans and mice. The breakpoints are frequently adjacent to the...

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Detalles Bibliográficos
Autores principales: Dorsett, Yair, Robbiani, Davide F., Jankovic, Mila, Reina-San-Martin, Bernardo, Eisenreich, Thomas R., Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118712/
https://www.ncbi.nlm.nih.gov/pubmed/17724134
http://dx.doi.org/10.1084/jem.20070884