Cargando…
Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation
After a brief period of antigenic stimulation, T cells become committed to a program of autonomous expansion and differentiation. We investigated the role of antigen-specific T cell precursor frequency as a possible cell-extrinsic factor impacting T cell programming in a model of allogeneic tissue t...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118720/ https://www.ncbi.nlm.nih.gov/pubmed/17261633 http://dx.doi.org/10.1084/jem.20062319 |