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Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation

After a brief period of antigenic stimulation, T cells become committed to a program of autonomous expansion and differentiation. We investigated the role of antigen-specific T cell precursor frequency as a possible cell-extrinsic factor impacting T cell programming in a model of allogeneic tissue t...

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Detalles Bibliográficos
Autores principales:	Ford, Mandy L., Koehn, Brent H., Wagener, Maylene E., Jiang, Wanhong, Gangappa, Shivaprakash, Pearson, Thomas C., Larsen, Christian P.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118720/ https://www.ncbi.nlm.nih.gov/pubmed/17261633 http://dx.doi.org/10.1084/jem.20062319

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