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Peroxisome proliferator–activated receptor (PPAR)α expression in T cells mediates gender differences in development of T cell–mediated autoimmunity

Peroxisome proliferator–activated receptor (PPAR)α is a nuclear receptor that mediates gender differences in lipid metabolism. PPARα also functions to control inflammatory responses by repressing the activity of nuclear factor κB (NF-κB) and c-jun in immune cells. Because PPARα is situated at the cr...

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Detalles Bibliográficos
Autores principales: Dunn, Shannon E., Ousman, Shalina S., Sobel, Raymond A., Zuniga, Luis, Baranzini, Sergio E., Youssef, Sawsan, Crowell, Andrea, Loh, John, Oksenberg, Jorge, Steinman, Lawrence
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118721/
https://www.ncbi.nlm.nih.gov/pubmed/17261635
http://dx.doi.org/10.1084/jem.20061839