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CD4(+)CD25(−)Foxp3(−) Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis
Nonhealing forms of leishmaniasis in humans are commonly associated with elevated levels of the deactivating cytokine IL-10, and in the mouse, normally chronic infections can be cleared in the absence of IL-10. Using a Leishmania major strain that produces nonhealing dermal lesions in a T helper typ...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118728/ https://www.ncbi.nlm.nih.gov/pubmed/17283207 http://dx.doi.org/10.1084/jem.20061886 |