Vascular wall–produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors

Prostanoids, bioactive lipids derived from arachidonic acid (AA), are important for vascular homeostasis. Among them, prostaglandin E2 (PGE2) enhances aggregation of platelets submaximally stimulated in vitro. This results from activation of EP3, one of the four PGE2 receptors, which decreases the t...

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Detalles Bibliográficos
Autores principales: Gross, Sabrina, Tilly, Peggy, Hentsch, Didier, Vonesch, Jean-Luc, Fabre, Jean-Etienne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118736/
https://www.ncbi.nlm.nih.gov/pubmed/17242161
http://dx.doi.org/10.1084/jem.20061617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118736/
https://www.ncbi.nlm.nih.gov/pubmed/17242161
http://dx.doi.org/10.1084/jem.20061617

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