WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

A large proportion of Wiskott-Aldrich syndrome (WAS) patients develop autoimmunity and allergy. CD4(+)CD25(+)FOXP3(+) natural regulatory T (nTreg) cells play a key role in peripheral tolerance to prevent immune responses to self-antigens and allergens. Therefore, we investigated the effect of WAS pr...

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Detalles Bibliográficos
Autores principales: Marangoni, Francesco, Trifari, Sara, Scaramuzza, Samantha, Panaroni, Cristina, Martino, Silvana, Notarangelo, Luigi D., Baz, Zeina, Metin, Ayse, Cattaneo, Federica, Villa, Anna, Aiuti, Alessandro, Battaglia, Manuela, Roncarolo, Maria-Grazia, Dupré, Loïc
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118740/
https://www.ncbi.nlm.nih.gov/pubmed/17296785
http://dx.doi.org/10.1084/jem.20061334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118740/
https://www.ncbi.nlm.nih.gov/pubmed/17296785
http://dx.doi.org/10.1084/jem.20061334

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