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Anti-CD4 mediates clonal anergy during transplantation tolerance induction
Depletion of CD4+ cells using anti-CD4 monoclonal antibodies leads to allograft tolerance. Here we show that anti-CD4-mediated tolerance to pancreatic islets of Langerhans transplanted from an A/J (IEk) donor to a diabetic C57B1/6 (B6) (IE-) recipient occurs in the absence of clonal deletion of the...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1991
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118801/ https://www.ncbi.nlm.nih.gov/pubmed/1899105 |