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Characterization of somatically mutated S107 VH11-encoded anti-DNA autoantibodies derived from autoimmune (NZB x NZW)F1 mice
We have studied 19 S107 heavy chain variable region gene (VH11)-encoded monoclonal antibodies from NZBWF1 mice. These studies show that a single VH gene can encode both antibodies to foreign antigens (anti- phosphorylcholine) and to self antigens (anti-double-stranded DNA) in the same animal. All of...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118831/ https://www.ncbi.nlm.nih.gov/pubmed/1900082 |