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T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice
Five islet-reactive T cell clones were established from islet- infiltrating T cells of non-obese diabetic (NOD) mice. All clones expressed CD4, but not CD8, and responded to islet cells from various strains of mice in the context of I-ANOD. They could induce insulitis when transferred into disease-r...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118862/ https://www.ncbi.nlm.nih.gov/pubmed/1902501 |