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Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant

Previous studies have demonstrated that insulin, like other protein antigens, requires processing in metabolically active antigen- presenting cells (APC) before it can be recognized by class II- restricted T lymphocytes. Unlike many other proteins, insulin peptides of minimal size retain the require...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119004/
https://www.ncbi.nlm.nih.gov/pubmed/1940793