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Structural differences between the two human complement C4 isotypes affect the humoral immune response
An animal model has been used to address the question of the biological importance of the known structural difference between the two isotypes of human C4, i.e., C4A and C4B. Guinea pigs deficient in C4 were reconstituted transiently with either human C4A or C4B protein and immunized with the bacter...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119129/ https://www.ncbi.nlm.nih.gov/pubmed/1732415 |