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Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells

To seek direct evidence for the notion that stem cells in the thymus need to be constantly replenished from the bone marrow (BM), fetal (day 15) thymuses from normal BALB/c mice were grafted into T and B cell- deficient C.B-17 SCID mice (both H-2d, I-E+). The thymus grafts in these mice showed norma...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119181/
https://www.ncbi.nlm.nih.gov/pubmed/1532413