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CD4+8- thymocytes bearing major histocompatibility complex class I- restricted T cell receptors: evidence for homeostatic control of early stages of CD4/CD8 lineage development

During thymus development CD4+ CD8+ precursor cells differentiate into mature CD4+ and CD8+ T cells expressing T cell receptors (TCR) that recognize foreign antigens in association with major histocompatibility complex (MHC) class II or I molecules, respectively. Studies with TCR transgenic mice hav...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119344/
https://www.ncbi.nlm.nih.gov/pubmed/1355104