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CD4+8- thymocytes bearing major histocompatibility complex class I- restricted T cell receptors: evidence for homeostatic control of early stages of CD4/CD8 lineage development
During thymus development CD4+ CD8+ precursor cells differentiate into mature CD4+ and CD8+ T cells expressing T cell receptors (TCR) that recognize foreign antigens in association with major histocompatibility complex (MHC) class II or I molecules, respectively. Studies with TCR transgenic mice hav...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119344/ https://www.ncbi.nlm.nih.gov/pubmed/1355104 |