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Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization
We used polyclonal antisera and monoclonal antibodies (mAbs) to inhibit the growth of clonal populations of two strains of Borrelia burgdorferi, the Lyme disease agent, and thereby select for antibody- resistant mutants. mAbs were directed at the outer membrane proteins, OspA or OspB. Mutants resist...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119346/ https://www.ncbi.nlm.nih.gov/pubmed/1339462 |