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Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization

We used polyclonal antisera and monoclonal antibodies (mAbs) to inhibit the growth of clonal populations of two strains of Borrelia burgdorferi, the Lyme disease agent, and thereby select for antibody- resistant mutants. mAbs were directed at the outer membrane proteins, OspA or OspB. Mutants resist...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119346/
https://www.ncbi.nlm.nih.gov/pubmed/1339462