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Lymphoproliferative disease in human peripheral blood mononuclear cell- injected SCID mice. I. T lymphocyte requirement for B cell tumor generation
Mechanisms of tumor development were studied in SCID mice injected with human lymphoid cells from Epstein-Barr virus-positive (EBV+) donors. About 80% of peripheral blood mononuclear cell (PBMC)-injected animals developed a lymphoproliferative disease associated with oligoclonal EBV+ tumors of human...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1992
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119452/ https://www.ncbi.nlm.nih.gov/pubmed/1460431 |