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The cytoplasmic domain mediates localization of furin to the trans- Golgi network en route to the endosomal/lysosomal system
To investigate the mechanisms of membrane protein localization to the Golgi complex, we have examined the intracellular trafficking of epitope-tagged forms of the mammalian endopeptidase, furin, in stably transformed rat basophilic leukemia cells. Our studies show that furin is predominantly localiz...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120164/ https://www.ncbi.nlm.nih.gov/pubmed/7914893 |