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Mitotic mechanisms in Alzheimer's disease?

The mechanism(s) leading to widespread hyper-phosphorylation of proteins in Alzheimer's disease (AD) are unknown. We have characterized seven new monoclonal antibodies recognizing independent phospho- epitopes in the paired helical filament proteins (PHF) found in AD brain. These antibodies sho...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2120731/
https://www.ncbi.nlm.nih.gov/pubmed/8636218