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Induction of insulin secretion in engineered liver cells by nitric oxide

BACKGROUND: Type 1 Diabetes Mellitus results from an autoimmune destruction of the pancreatic beta cells, which produce insulin. The lack of insulin leads to chronic hyperglycemia and secondary complications, such as cardiovascular disease. The currently approved clinical treatments for diabetes mel...

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Detalles Bibliográficos
Autores principales: Muniappan, Latha, Özcan, Sabire
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121102/
https://www.ncbi.nlm.nih.gov/pubmed/17941991
http://dx.doi.org/10.1186/1472-6793-7-11