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The foxa2 Gene Controls the Birth and Spontaneous Degeneration of Dopamine Neurons in Old Age

Parkinson disease affects more than 1% of the population over 60 y old. The dominant models for Parkinson disease are based on the use of chemical toxins to kill dopamine neurons, but do not address the risk factors that normally increase with age. Forkhead transcription factors are critical regulat...

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Detalles Bibliográficos
Autores principales: Kittappa, Raja, Chang, Wendy W, Awatramani, Rajeshwar B, McKay, Ronald D. G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121110/
https://www.ncbi.nlm.nih.gov/pubmed/18076286
http://dx.doi.org/10.1371/journal.pbio.0050325