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d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia
The N-methyl-d-aspartate receptor co-agonist d-serine is synthesized by serine racemase and degraded by d-amino acid oxidase. Both d-serine and its metabolizing enzymes are implicated in N-methyl-d-aspartate receptor hypofunction thought to occur in schizophrenia. We studied d-amino acid oxidase and...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121142/ https://www.ncbi.nlm.nih.gov/pubmed/17880399 http://dx.doi.org/10.1111/j.1460-9568.2007.05769.x |