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A comparison of immunogenicity and protective immunity against experimental plague by intranasal and/or combined with oral immunization of mice with attenuated Salmonella serovar Typhimurium expressing secreted Yersinia pestis F1 and V antigen

We investigated the relative immunogenicity and protective efficacy of recombinant X85MF1 and X85V strains of ΔcyaΔcrpΔasd-attenuated Salmonella Typhimurium expressing, respectively, secreted Yersinia pestis F1 and V antigens, following intranasal (i.n.) or i.n. combined with oral immunization for a...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Tssann, Hsu, Hui-Ling, Liang, Chung-Chih, Chuang, Chuan-Chang, Lin, Huang-Chi, Liu, Yu-Tien
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121146/
https://www.ncbi.nlm.nih.gov/pubmed/17640293
http://dx.doi.org/10.1111/j.1574-695X.2007.00280.x