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Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

There is a remarkable heterogeneity in the functional profile (quality) of T cell responses. Importantly, the magnitude and/or quality of a response required for protection may be different depending on the infection. Here, we assessed the capacity of different Toll like receptor (TLR)-binding compo...

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Detalles Bibliográficos
Autores principales: Wille-Reece, Ulrike, Flynn, Barbara J., Loré, Karin, Koup, Richard A., Miles, Aaron P., Saul, Allan, Kedl, Ross M., Mattapallil, Joseph J., Weiss, Walter R., Roederer, Mario, Seder, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121207/
https://www.ncbi.nlm.nih.gov/pubmed/16636134
http://dx.doi.org/10.1084/jem.20052433