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A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis

Telomerase is a ribonucleoprotein complex consisting of two essential core components: a reverse transcriptase and an RNA subunit (telomerase RNA [TR]). Dysregulation of telomerase has been associated with cell immortalization and oncogenesis. Marek's disease herpesvirus (MDV) induces a maligna...

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Detalles Bibliográficos
Autores principales: Trapp, Sascha, Parcells, Mark S., Kamil, Jeremy P., Schumacher, Daniel, Tischer, B. Karsten, Kumar, Pankaj M., Nair, Venugopal K., Osterrieder, Nikolaus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121211/
https://www.ncbi.nlm.nih.gov/pubmed/16651385
http://dx.doi.org/10.1084/jem.20052240