Cargando…
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
The helix-loop-helix protein, E47, is essential for both B- and T-lineage development. Here we demonstrate that in vitro E47 and Notch signaling act in concert to promote T cell development from fetal hematopoieitic progenitors and to restrain development into the natural killer and myeloid cell lin...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121213/ https://www.ncbi.nlm.nih.gov/pubmed/16682500 http://dx.doi.org/10.1084/jem.20060268 |