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Protective immune responses against West Nile virus are primed by distinct complement activation pathways

West Nile virus (WNV) causes a severe infection of the central nervous system in several vertebrate animals including humans. Prior studies have shown that complement plays a critical role in controlling WNV infection in complement (C) 3(−/−) and complement receptor 1/2(−/−) mice. Here, we dissect t...

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Detalles Bibliográficos
Autores principales: Mehlhop, Erin, Diamond, Michael S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121216/
https://www.ncbi.nlm.nih.gov/pubmed/16651386
http://dx.doi.org/10.1084/jem.20052388