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Effects of STI571 (gleevec) on pancreatic cancer cell growth

BACKGROUND: Pancreatic cancer is an aggressive malignancy characterized by low responsiveness to chemotherapy and radiotherapy. This resistance is partly due to the overexpression of several tyrosine kinase receptors and their ligands. STI571 has specific activity in inhibiting c-kit, PDGF and Abl r...

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Detalles Bibliográficos
Autores principales: Li, Junsheng, Kleeff, Jörg, Guo, Junchao, Fischer, Lars, Giese, Nathalia, Büchler, Markus W, Friess, Helmut
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212230/
https://www.ncbi.nlm.nih.gov/pubmed/14521721
http://dx.doi.org/10.1186/1476-4598-2-32