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Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells

BACKGROUND: Astrocytomas are the most common type of primary central nervous system tumors. They are frequently associated with genetic mutations that deregulate cell cycle and render these tumors resistant to apoptosis. STAT3, signal transducer and activator of transcription 3, participates in seve...

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Detalles Bibliográficos
Autores principales: Konnikova, Liza, Kotecki, Maciej, Kruger, Mathew M, Cochran, Brent H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212316/
https://www.ncbi.nlm.nih.gov/pubmed/13678425
http://dx.doi.org/10.1186/1471-2407-3-23