Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties

BACKGROUND: Non-viral vectors for gene transfer are less immunogenic than viral vectors but also less efficient. Significant effort has focused on enhancing non-viral gene transfer efficiency by increasing nuclear import of plasmid DNA, particularly by coupling nuclear localization peptidic sequence...

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Detalles Bibliográficos
Autores principales: Carrière, Marie, Escriou, Virginie, Savarin, Aline, Scherman, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212318/
https://www.ncbi.nlm.nih.gov/pubmed/12969505
http://dx.doi.org/10.1186/1472-6750-3-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212318/
https://www.ncbi.nlm.nih.gov/pubmed/12969505
http://dx.doi.org/10.1186/1472-6750-3-14

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