Cargando…
The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway
Wnt signaling plays an important role in both oncogenesis and development. Activation of the Wnt pathway results in stabilization of the transcriptional coactivator β-catenin. Recent studies have demonstrated that axin, which coordinates β-catenin degradation, is itself degraded. Although the key mo...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2003
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212691/ https://www.ncbi.nlm.nih.gov/pubmed/14551908 http://dx.doi.org/10.1371/journal.pbio.0000010 |