Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions

RNA-mediated interference (RNAi) is a method to inhibit gene function by introduction of double-stranded RNA (dsRNA). Recently, an RNAi library was constructed that consists of bacterial clones expressing dsRNA, corresponding to nearly 90% of the 19,427 predicted genes of C. elegans. Feeding of this...

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Detalles Bibliográficos
Autores principales: Simmer, Femke, Moorman, Celine, van der Linden, Alexander M, Kuijk, Ewart, van den Berghe, Peter V.E, Kamath, Ravi S, Fraser, Andrew G, Ahringer, Julie, Plasterk, Ronald H. A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212692/
https://www.ncbi.nlm.nih.gov/pubmed/14551910
http://dx.doi.org/10.1371/journal.pbio.0000012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212692/
https://www.ncbi.nlm.nih.gov/pubmed/14551910
http://dx.doi.org/10.1371/journal.pbio.0000012

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