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Genome-Wide RNAi of C. elegans Using the Hypersensitive rrf-3 Strain Reveals Novel Gene Functions
RNA-mediated interference (RNAi) is a method to inhibit gene function by introduction of double-stranded RNA (dsRNA). Recently, an RNAi library was constructed that consists of bacterial clones expressing dsRNA, corresponding to nearly 90% of the 19,427 predicted genes of C. elegans. Feeding of this...
Autores principales: | Simmer, Femke, Moorman, Celine, van der Linden, Alexander M, Kuijk, Ewart, van den Berghe, Peter V.E, Kamath, Ravi S, Fraser, Andrew G, Ahringer, Julie, Plasterk, Ronald H. A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212692/ https://www.ncbi.nlm.nih.gov/pubmed/14551910 http://dx.doi.org/10.1371/journal.pbio.0000012 |
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