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Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action

Type 2 diabetes is an increasingly common, serious metabolic disorder with a substantial inherited component. It is characterised by defects in both insulin secretion and action. Progress in identification of specific genetic variants predisposing to the disease has been limited. To complement ongoi...

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Detalles Bibliográficos
Autores principales: Barroso, Inês, Luan, Jian'an, Middelberg, Rita P. S, Harding, Anne-Helen, Franks, Paul W, Jakes, Rupert W, Clayton, David, Schafer, Alan J, O'Rahilly, Stephen, Wareham, Nicholas J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC212698/
https://www.ncbi.nlm.nih.gov/pubmed/14551916
http://dx.doi.org/10.1371/journal.pbio.0000020