Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting

BACKGROUND: To replicate, lentiviruses such as HIV must integrate DNA copies of their RNA genomes into host cell chromosomes. Lentiviral integration is favored in active transcription units, which allows efficient viral gene expression after integration, but the mechanisms directing integration targ...

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Detalles Bibliográficos
Autores principales: Marshall, Heather M., Ronen, Keshet, Berry, Charles, Llano, Manuel, Sutherland, Heidi, Saenz, Dyana, Bickmore, Wendy, Poeschla, Eric, Bushman, Frederic D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129110/
https://www.ncbi.nlm.nih.gov/pubmed/18092005
http://dx.doi.org/10.1371/journal.pone.0001340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129110/
https://www.ncbi.nlm.nih.gov/pubmed/18092005
http://dx.doi.org/10.1371/journal.pone.0001340

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