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Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide

BACKGROUND: Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a neurotoxic peptide containing amino acids 105–132 of t...

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Detalles Bibliográficos
Autores principales: Wilson, Rona, Bate, Clive, Boshuizen, Ronald, Williams, Alun, Brewer, James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131757/
https://www.ncbi.nlm.nih.gov/pubmed/18034899
http://dx.doi.org/10.1186/1471-2202-8-99