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Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide
BACKGROUND: Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a neurotoxic peptide containing amino acids 105–132 of t...
Autores principales: | Wilson, Rona, Bate, Clive, Boshuizen, Ronald, Williams, Alun, Brewer, James |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2131757/ https://www.ncbi.nlm.nih.gov/pubmed/18034899 http://dx.doi.org/10.1186/1471-2202-8-99 |
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